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These side effects should decrease once the body adjusts to the medicine. Along with its needed effects, a medicine may cause some unwanted effects. Spironolactone is safe when used under a doctor's supervision.
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Spironolactone: How It Helps Treat Hair Loss in Women
It’s also important to note that hair loss has been reported as a side effect of Aldactone. But it’s not known exactly how many people may have had this side effect in clinical trials. Aldactone isn’t FDA-approved to treat hair loss, but the drug may be prescribed off-label for this purpose. Aldactone isn’t FDA-approved to treat acne, but the drug is sometimes prescribed off-label to treat this condition.
Dosage for heart failure
As with most drugs, some people can have an allergic reaction after taking spironolactone oral tablets. You’re also more likely to have this side effect if you take spironolactone with potassium supplements or other medications that increase your potassium level. Eating lots of potassium-rich foods, especially salt substitutes that contain potassium, also increases your risk for hyperkalemia. See the “Spironolactone interactions” section below to read more about this risk.
substantial weight loss over a short period of time
The goal of feminizing hormone therapy is the development of female sex characteristics and minimization of male secondary sex characteristics. Suppression and blocking of the male hormone testosterone leads to the suppression of male sexual characteristics and spironolactone is the most commonly used androgen blocker. Spironolactone oral solution is therapeutically different from spironolactone tablets. Before switching formats, get a new prescription from a doctor or other healthcare professional.
Possible Side Effects
I am finally off Spiro after a few years of beautiful, perfect skin (sigh). It was prescribed for my persistent cystic hormal acne -- something I've dealt with since my teens but mostly in my adult life. I only ever get it in one part of my face (chin and sides of chin) and they usually require cortisone injections, so this was to be preventative. It worked SOOO well for my skin, like nothing including accutane ever had. Like most people on it, I've had docs continually telling me it can't cause hair loss, along with a few docs who have said it can. I saw the PA, who prescribed the spiro, for a hair loss appt.
What drug class does spironolactone belong to? Is it a blood thinner?
Long-term use of spironolactone is largely limited to relatively severe medical conditions, so the benefits of spironolactone often outweigh the risks. For some people with certain medical conditions, those risks may be too much for comfort. As a diuretic, spironolactone increases the body’s elimination of water, temporarily decreasing body weight. This is not, however, real weight loss in terms of fat or other body tissues. Studies on women with polycystic ovary syndrome suggest that spironolactone may improve carbohydrate metabolism, but not by much. If any of the signs or symptoms of high blood potassium are experienced while taking spironolactone, get immediate medical attention.
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Aldactone for high blood pressure
A class of drugs is a group of medications that work in a similar way. Spironolactone belongs to a class of drugs called aldosterone antagonists. If you have weight loss with spironolactone, it usually indicates that the medication is working for you. But if you’re concerned about weight loss with this drug, talk with your doctor. They can check to see if the medication or something else is causing you to lose weight.
Special Health Reports
Off-label use is when a drug that’s approved to treat one condition is used to treat a different condition. One is to help manage edema (swelling and fluid retention). The second is to lower the risk of a hospital stay due to heart failure.
THE LEADING MEDICAL
Drug-induced liver and kidney injury could evolve into long-term or lifelong medical conditions. Many other studies and case reports have also reported better efficacy of this combined therapy for androgenetic alopecia. Furthermore, in a similar case series of six adolescents found an evident improvement in five of them using the combination of oral minoxidil and spironolactone [18].
If you cannot have surgery, your doctor may give you the lowest effective dose of this drug long term. The typical starting dosage is 25 mg taken by mouth once per day. Your doctor may increase or decrease your dosage based on how you respond to the drug. Some people may take 50 mg once per day, and others may take 25 mg once every other day. Taking digoxin (Lanoxin) with spironolactone may increase the effects of digoxin.
These symptoms can include muscle weakness, fatigue, nausea, vomiting, tingling, trouble breathing, heart palpitations, irregular heartbeats, and chest pain. Spironolactone is a medication usually used for fluid retention but sometimes used to treat a specific type of hair loss. Currently, spironolactone is administered by prescription and is taken orally and/or compounded into topical formulations for hair loss with fewer side effects. Spironolactone slows down the production of androgens or testosterone hormones that are mainly responsible for hair loss, according to Gonzalez.
They may be able to choose a medicine that doesn’t cause the same side effect. Your doctor may also recommend that you stop taking the medication for a few months. Gout medications like allopurinol (Zyloprim and Lopurin) have been reported to cause hair loss.
Two studies4,10 treated with topical spironolactone gels or solutions included a total of 65 men and 115 women, and there was no significant difference in gender between the groups reported. So long story short, I've been off it for 2 full weeks after tapering down for a few months, and my hair is coming out in clumps. I know it has only been 2 weeks since fully stopping, but I really need to hear from some women with success stopping and having their hair return to normal. For what its worth, in response to the questioner, YES I've noticed it and experienced it, you are not crazy. I use Nizoral and have felt that it helps keep me from losing hair, but just a little bit, and doesn't encourage re-growth (I don't think?).
I have never suffered with any type of hair loss and I’m not taking any other medication that could be causing this. If you’re interested in using Aldactone for female pattern hair loss, talk with your doctor. If you’re interested in finding an alternative to spironolactone oral tablets, talk with your doctor.
The dosing regimen and treatments used were also variable across studies (Table (Table1).1). The risk of bias assessment results are summarized in the supplementary tables given in Appendix 2. We conducted a systematic review and meta-analysis of randomized controlled trials and observational studies that assessed the efficacy and safety of oral spironolactone for treating hair loss. We searched for eligible papers in PubMed, Web of Science (ISI), Embase, and Scopus.